1 Introduction
Claus Bachert and Luo Zhang
2 Epidemiology
Xiangdong Wang, Ming Zheng, and Luo Zhang
3 Quality of Life and Psychological Burden
Eduardo Lehrer, Mauricio López-Chacón, Isam Alobid
and Joaquim Mullol
4 Genetics and Epigenetics
Jingyun Li, Luo Zhang, and Yuan Zhang
5 Involvement of the Immune System in Airways Disease
Wei Wang and Ying Sun
6 T Cells and Group 2 Innate Lymphoid Cells 2
Atsushi Kato and Robert P. Schleimer
7 B Cells and Plasma Cells
Siobhan Ward, Zeynep Celebi S?zener, and Mübeccel Akdis
8 Eosinophils
Elien Gevaert
9 Neutrophils
Elien Gevaert
10 Remodeling Features
Lili Shi and Zheng Liu
11 Nasal Mucociliary Clearance
Jian Jiao and Luo Zhang
12 Sinonasal Epithelium
Michael Soyka and Cezmi A. Akdis
13 Microbiology
Mahboobeh Mahdavinia and Robert P. Schleimer
14 Staphylococcus aureus and Its Proteins
Goran Abdurrahman and Barbara M. Br?ker
15 Viruses
Feng Lan and Luo Zhang
16 Environmental and Allergic Triggers
Changyu Qiu and Lei Cheng
17 Dysfunctional Immune Regulatory System
Jinmei Xue, Pingchang Yang, and Changqing Zhao
18 Chronic Rhinosinusitis with and Without Nasal Polyps
Bradley F. Marple
19 Allergic Fungal Sinusitis
Fenghong Chen, Matthew W. Ryan, and Bradley F. Marple
20 Type 2 Immune Reactions and Consequences
Claus Bachert
21 Regional Difference
Kun Du and Xiangdong Wang
22 Multimorbidities
David Bedoya, Cristóbal Langdon, Isam Alobid, José Antonio
Castillo, and Joaquim Mullol
23 Clinical Diagnosis and Phenotypes
Kevin Hur and Robert C. Kern
24 Imaging the Anatomic Landmarks for Safe FESS
Simion James Zinreich and Sachin K. Gujar
25 Olfactory Function Assessment
Meritxell Valls-Mateus, Franklin Mari?o-Sánchez, Isam
Alobid, Concepció Marin, and Joaquim Mullol
26 Local and Systemic Biomarkers
Nan Zhang
27 Benign Tumors of the Nose and Sinuses
Manuel Bernal-Sprekelsen
28 Sinonasal Inverted Papilloma
Chengshuo Wang, Siyuan Ma, and Luo Zhang
29 Malignant Tumors of the Nose and Sinuses
Manuel Bernal-Sprekelsen and Isam Alobid
30 Pediatric Chronic Rhinosinusitis: View from Europe
Thibaut van Zele
31 Pediatric Chronic Sinusitis: View from China
Jingying Ma and Bing Zhou
32 Wegener’s Granulomatosis
Jichao Sha and Dongdong Zhu
33 IgG4-Related Disorders
Yingshi Piao
34 Eosinophilic Granulomatosis with Polyangiitis
Yujie Cao and Huabin Li
35 Oral Corticosteroids
Chengshuo Wang, Yifan Meng, and Luo Zhang
36 Nasal Spray Corticosteroids
Yujie Cao, Huabin Li, and Dehui Wang
37 Nebulization Corticosteroids
Chengshuo Wang, Yifan Meng, and Luo Zhang
38 Steroid-Eluting Stent Placement
Chengshuo Wang, Longgang Yu, and Luo Zhang
39 Steroid Infiltrated Packing Materials
Yueqi Sun and Jianbo Shi
40 Corticosteroids Resistance
Yujie Cao, Dehui Wang, and Huabin Li
41 Leukotriene Receptor Antagonists
Rui Zheng, Tian Yuan, and Qintai Yang
42 Antihistamine
Hongfei Lou, Yanran Huang, and Luo Zhang
43 Antibiotics
Dawei Wu and Yongxiang Wei
44 Decongestant and Nasal Irrigation
Xiaoping Lai and Gehua Zhang
45 Probiotics, Bacterial Lysates, and Proton Pump Inhibitors
Luping Zhu and Lei Cheng
46 Impact of Endotyping on the Indication for Surgery
Claus Bachert
47 Surgical Procedures
Ashleigh Halderman and Bradley F. Marple
48 Reboot Surgery
Claus Bachert
49 Complications of Endoscopic Sinus Surgery
Yi Dong and Bing Zhou
50 Peri-operative Management
Jian Li and Weiping Wen
51 Surgery Outcome and Predictors
Fenghong Chen and Jianbo Shi
52 Biologics in Chronic Rhinosinusitis with Nasal Polyps
Claus Bachert
53 Integrated Care Pathways
Claus Bachert and Nan Zhang
54 Unmet Needs
Luo Zhang and Claus Bachert
Correction to: Staphylococcus aureus and Its Proteins /C
Goran Abdurrahman and Barbara M. Br?ker
Index